Chloride → 2-(3-Fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid (5-methanesulfonyl-indol-1-yl)-amide
Reaction equation
[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:29][S:30](=[O:31])(=[O:32])[c:33]1[cH:34][c:35]2[cH:36][cH:37][n:38]([NH2:42])[c:39]2[cH:40][cH:41]1.[CH3:2][Si:3]([N-:4][Si:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[CH3:10].[Cl-:11].[F:12][c:13]1[cH:14][c:15](-[c:19]2[n:20][cH:21][c:22]([C:26](=[O:27])[OH:28])[c:23]([CH3:25])[n:24]2)[cH:16][cH:17][cH:18]1.[Na+:1].[cH:48]1[cH:49][cH:50][n:51][cH:52][cH:53]1>>[F:12][c:13]1[cH:14][c:15](-[c:19]2[n:20][cH:21][c:22]([C:26](=[O:28])[NH:42][n:38]3[cH:37][cH:36][c:35]4[cH:34][c:33]([S:30]([CH3:29])(=[O:31])=[O:32])[cH:41][cH:40][c:39]43)[c:23]([CH3:25])[n:24]2)[cH:16][cH:17][cH:18]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a04dc54b5ea843b19018d94ee3657981
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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