Sodium ion → 2-[5-(4-Amino-3-nitro-5-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([N+:14](=[O:15])[O-:16])[c:5]([NH2:6])[c:7]([CH:9]2[O:10][CH2:11][CH2:12][CH2:13]2)[cH:8]1.[C:134]([O:135][CH3:136])([CH3:137])([CH3:138])[CH3:139].[C:42](=[O:43])([O-:44])[O-:45].[CH2:17]1[O:18][CH2:19][CH2:20][O:21][CH2:22]1.[CH3:23][C:24]1([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29][B:30]([c:31]2[cH:32][n:33][c:34]([C:37]([CH3:38])([CH3:39])[OH:40])[n:35][cH:36]2)[O:41]1.[CH3:48][CH2:49][O:50][C:51]([CH3:52])=[O:53].[Cl:54][CH2:55][Cl:56].[Na+:46].[Na+:47].[cH:57]1[cH:58][cH:59][c:60]([P:61]([Pd:62]([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)([P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[P:101]([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)([c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)([c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)[c:126]2[cH:127][cH:128][cH:129][cH:130][cH:131]2)[cH:132][cH:133]1>>[c:2]1(-[c:31]2[cH:32][n:33][c:34]([C:37]([CH3:38])([CH3:39])[OH:40])[n:35][cH:36]2)[cH:3][c:4]([N+:14](=[O:15])[O-:16])[c:5]([NH2:6])[c:7]([CH:9]2[O:10][CH2:11][CH2:12][CH2:13]2)[cH:8]1Participants
10
Reactant 9
HCID 923Sodium ion2×
HCID 6344Dichloromethane
HCID 8857Ethyl Acetate
HCID 15413tert-Butyl methyl ether
HCID 19660Carbonate Ion
HCID 312751,4-Dioxane
HCID 665203402-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]propan-2-ol
HCID 681084754-Bromo-2-nitro-6-tetrahydrofuran-2-yl-aniline
HCID 178420554HCID 178420554, compoundProduct 1
Sources & evidence
- ORD record
- ord-6e921ab59a2e427a9aac384fc72d37eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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