Trifluoroacetic acid → Hydrochloric Acid

HRID 2135421Notes

Reaction equation

HRID 2135421 reaction equation
[Cl:57][c:58]1[n:59][c:60]([NH:79][CH2:80][CH:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[c:61]2[n:62][cH:63][n:64]([CH:67]3[CH:68]([OH:78])[CH:69]([OH:77])[CH:70]([NH:72][C:73]([CH2:74][CH3:75])=[O:76])[CH2:71]3)[c:65]2[n:66]1.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[N:94]1([CH:99]2[CH2:100][NH:101][CH2:102][CH2:103]2)[CH2:95][CH2:96][CH2:97][CH2:98]1.[NH2:8][CH:9]1[CH2:10][CH2:11][N:12]([c:13]2[n:14][c:15]3[c:16]([n:17][cH:18][n:19]3[CH:20]3[CH2:21][CH:22]([NH:23][C:24](=[O:25])[CH2:26][O:27][CH2:28][c:29]4[cH:30][cH:31][cH:32][cH:33][cH:34]4)[CH:35]([OH:36])[CH:37]3[OH:38])[c:39]([NH:40][CH2:41][CH:42]([c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[c:49]3[cH:50][cH:51][cH:52][cH:53][cH:54]3)[n:55]2)[CH2:56]1>>[ClH:57].[c:58]1([N:101]2[CH2:100][CH:99]([N:94]3[CH2:95][CH2:96][CH2:97][CH2:98]3)[CH2:103][CH2:102]2)[n:59][c:60]([NH:79][CH2:80][CH:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[c:61]2[n:62][cH:63][n:64]([CH:67]3[CH:68]([OH:78])[CH:69]([OH:77])[CH:70]([NH:72][C:73]([CH2:74][CH3:75])=[O:76])[CH2:71]3)[c:65]2[n:66]1

Participants

6

Reactant 4

HCID 6422Trifluoroacetic acidHCID 146273751-(Pyrrolidin-3-yl)pyrrolidineHCID 87240175N-[4-[2-chloro-6-(2,2-diphenylethylamino)purin-9-yl]-2,3-dihydroxycyclopentyl]propanamideHCID 178507880HCID 178507880, compound

Product 2

HCID 313Hydrochloric AcidHCID 178460048N-[4-[6-(2,2-diphenylethylamino)-2-(3-pyrrolidin-1-ylpyrrolidin-1-yl)purin-9-yl]-2,3-dihydroxycyclopentyl]propanamide

Sources & evidence

ORD record
ord-de3a647780f3420882c585e7c112aa11
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…