Ethanolamine → N-(2-hydroxyethyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole-5-carboxamide

HRID 2135570Notes

Reaction equation

HRID 2135570 reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[NH2:29][CH2:30][CH2:31][OH:32].[O:1]1[CH2:2][CH2:3][CH:4]([CH2:7][n:8]2[cH:9][c:10]([C:20](=[O:21])[CH:22]3[C:23]([CH3:27])([CH3:28])[C:24]3([CH3:25])[CH3:26])[c:11]3[cH:12][c:13]([C:17](=[O:18])[OH:19])[cH:14][cH:15][c:16]23)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][CH:4]([CH2:7][n:8]2[cH:9][c:10]([C:20](=[O:21])[CH:22]3[C:23]([CH3:27])([CH3:28])[C:24]3([CH3:25])[CH3:26])[c:11]3[cH:12][c:13]([C:17](=[O:18])[NH:29][CH2:30][CH2:31][OH:32])[cH:14][cH:15][c:16]23)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 700EthanolamineHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 67269817HCID 67269817, compound

Product 1

HCID 67269831N-(2-hydroxyethyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole-5-carboxamide

Sources & evidence

ORD record
ord-ba15861665f94408b7550755c1e93d81
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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