Toluene → 1-(2,5-Difluoro-4-methoxyphenyl)piperazine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH3:7])[c:8]([CH3:9])[cH:10]1.[Br:25][c:26]1[cH:27][c:28]([F:35])[c:29]([O:33][CH3:34])[cH:30][c:31]1[F:32].[CH2:36]1[NH:37][CH2:38][CH2:39][NH:40][CH2:41]1.[CH3:11][CH2:12][c:13]1[cH:14][cH:15][cH:16][cH:17][c:18]1[N:19]1[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1.[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[CH3:49][CH2:50][O:51][C:52](=[O:53])[CH3:54]>>[N:19]1([c:26]2[cH:27][c:28]([F:35])[c:29]([O:33][CH3:34])[cH:30][c:31]2[F:32])[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1Participants
7
Sources & evidence
- ORD record
- ord-83907d0223544b5cb114bc31f2e59500
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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