Methanol → Trifluoroacetic acid

HRID 2135703Notes

Reaction equation

HRID 2135703 reaction equation
[CH3:18][OH:19].[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH:8]1[CH2:9][C:10]([c:13]2[s:14][cH:15][cH:16][n:17]2)=[CH:11][CH2:12]1.[Pt:20](=[O:21])=[O:22]>>[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH:8]1[CH2:9][CH:10]([c:13]2[s:14][cH:15][cH:16][n:17]2)[CH2:11][CH2:12]1

Participants

6

Reactant 4

HCID 887MethanolHCID 6422Trifluoroacetic acidHCID 345198Adams' catalystHCID 59443791HCID 59443791, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 552194372-(Pyrrolidin-3-yl)-1,3-thiazole

Sources & evidence

ORD record
ord-22323850753f434baa5d704a6c1cfe93
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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