Tetrahydrofuran → [Tert-butoxycarbonylimino-(4-hydroxy-piperidin-1-yl)-methyl]-carbamic acid tert-butyl ester

HRID 2135918Notes

Reaction equation

HRID 2135918 reaction equation
[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13]([NH:14][C:15]([n:16]1[cH:17][cH:18][cH:19][n:20]1)=[N:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:15](=[N:14][C:13]([O:12][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:29])[NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 79341Piperidin-4-olHCID 4428040N,N'-Bis(tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine

Product 1

HCID 67271828[Tert-butoxycarbonylimino-(4-hydroxy-piperidin-1-yl)-methyl]-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-2398ad595f4a4f37b67dde40730942fd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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