Dimethyl Sulfoxide → Gatifloxacin

HRID 2136430Notes

Reaction equation

HRID 2136430 reaction equation
[CH3:22][CH:23]1[NH:24][CH2:25][CH2:26][NH:27][CH2:28]1.[CH3:30][S:31]([CH3:32])=[O:33].[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[cH:9][c:10]([F:17])[c:11]([F:16])[c:12]([O:14][CH3:15])[c:13]23)[CH2:2][CH2:3]1.[OH2:29]>>[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[cH:9][c:10]([F:17])[c:11]([N:27]4[CH2:26][CH2:25][NH:24][CH:23]([CH3:22])[CH2:28]4)[c:12]([O:14][CH3:15])[c:13]23)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 660572-MethylpiperazineHCID 70194651-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

Product 1

HCID 5379Gatifloxacin

Sources & evidence

ORD record
ord-ba372a1aed3a49d39b5d9151a2865fdb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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