Acetate → (8-Methyl-2-phenylquinolin-3-yl)methanol

HRID 2136701Notes

Reaction equation

HRID 2136701 reaction equation
[CH3:49][O:50][CH2:51][CH2:52][O:53][CH3:54].[Cl:1][c:2]1[n:3][c:4]2[c:5]([CH3:14])[cH:6][cH:7][cH:8][c:9]2[cH:10][c:11]1[CH2:12][OH:13].[K+:15].[K+:16].[O-:17][C:18]([O-:19])=[O:20].[O-:57][C:58]([CH3:59])=[O:60].[O-:61][C:62]([CH3:63])=[O:64].[OH2:55].[OH:21][B:22]([OH:23])[c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[Pd+2:56].[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[c:2]1(-[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[n:3][c:4]2[c:5]([CH3:14])[cH:6][cH:7][cH:8][c:9]2[cH:10][c:11]1[CH2:12][OH:13]

Participants

10

Reactant 9

HCID 175Acetate2×HCID 813Potassium Cation2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 66827Phenylboronic AcidHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 865104(2-Chloro-8-methylquinolin-3-yl)methanol

Product 1

HCID 57707842(8-Methyl-2-phenylquinolin-3-yl)methanol

Sources & evidence

ORD record
ord-f1298d2d376c40bb960055cd41e48484
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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