Hydrochloric Acid → N4-(3-ethynylphenyl)quinazoline-4,7-diamine

HRID 213803Notes

Reaction equation

HRID 213803 reaction equation
[C:2](#[CH:3])[c:4]1[cH:5][c:6]([NH:10][c:11]2[n:12][cH:13][n:14][c:15]3[cH:16][c:17]([N+:21]([O-:22])=[O:23])[cH:18][cH:19][c:20]23)[cH:7][cH:8][cH:9]1.[CH3:24][OH:25].[CH:26]([Cl:27])([Cl:28])[Cl:29].[ClH:1].[Na+:34].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1.[OH2:40].[P:30]([O-:31])([OH:32])[OH:33]>>[C:2](#[CH:3])[c:4]1[cH:5][c:6]([NH:10][c:11]2[n:12][cH:13][n:14][c:15]3[cH:16][c:17]([NH2:21])[cH:18][cH:19][c:20]23)[cH:7][cH:8][cH:9]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 962WaterHCID 6212ChloroformHCID 8028TetrahydrofuranHCID 5460622Dihydrogen phosphiteHCID 16045519N-(3-ethynylphenyl)-7-nitroquinazolin-4-amine

Product 1

HCID 16045588N4-(3-ethynylphenyl)quinazoline-4,7-diamine

Sources & evidence

ORD record
ord-f012aa2018584cb0be56e85c6b5d35f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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