Pyridine → 4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic acid 3,5-dichloro-benzylamide
Reaction equation
[CH3:39][N:40]([c:41]1[cH:42][cH:43][n:44][cH:45][cH:46]1)[CH3:47].[Cl:24][c:25]1[cH:26][c:27]([CH2:28][NH2:29])[cH:30][c:31]([Cl:33])[cH:32]1.[I:7][c:8]1[cH:9][cH:10][c:11]([C:14]2([C:21](=[O:22])[OH:23])[CH2:15][CH2:16][N:17]([CH3:20])[CH2:18][CH2:19]2)[cH:12][cH:13]1.[O:34]=[CH:35][N:36]([CH3:37])[CH3:38].[n:1]1[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[I:7][c:8]1[cH:9][cH:10][c:11]([C:14]2([C:21](=[O:23])[NH:29][CH2:28][c:27]3[cH:26][c:25]([Cl:24])[cH:32][c:31]([Cl:33])[cH:30]3)[CH2:15][CH2:16][N:17]([CH3:20])[CH2:18][CH2:19]2)[cH:12][cH:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2afa215fea554c3fad6c4c25de628c8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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