Triethylamine → 5-{9-Isobutyl-8-[4-(methylsulfonyl)piperazin-1-yl]-6-morpholin-4-yl-9H-purin-2-yl}pyrimidin-2-amine
Reaction equation
[CH2:13]([CH:14]([CH3:15])[CH3:16])[n:17]1[c:18]2[n:19][c:20](-[c:38]3[cH:39][n:40][c:41]([NH2:44])[n:42][cH:43]3)[n:21][c:22]([N:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[c:23]2[n:24][c:25]1[N:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:45][N:46]1[CH2:47][CH2:48][CH2:49][C:50]1=[O:51].[S:8](=[O:9])(=[O:10])([CH3:11])[Cl:12]>>[S:8](=[O:9])(=[O:10])([CH3:11])[N:29]1[CH2:28][CH2:27][N:26]([c:25]2[n:17]([CH2:13][CH:14]([CH3:15])[CH3:16])[c:18]3[n:19][c:20](-[c:38]4[cH:39][n:40][c:41]([NH2:44])[n:42][cH:43]4)[n:21][c:22]([N:32]4[CH2:33][CH2:34][O:35][CH2:36][CH2:37]4)[c:23]3[n:24]2)[CH2:31][CH2:30]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-a634e4e09c31407c8602dd6554122cac
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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