Sodium ion → ethyl 4-[tert-butyl(dimethyl)silyl]oxy-2-[[4-(4-fluorophenyl)piperidin-1-yl]methyl]cyclopentane-1-carboxylate

HRID 213863Notes

Reaction equation

HRID 213863 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH:7]([CH2:19][O:20][S:21]([c:22]2[cH:23][cH:24][c:25]([CH3:26])[cH:27][cH:28]2)(=[O:29])=[O:30])[CH2:8][CH:9]([O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10]1.[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[CH3:53][N:54]([CH3:55])[CH:56]=[O:57].[F:31][c:32]1[cH:33][cH:34][c:35]([CH:38]2[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]2)[cH:36][cH:37]1.[I-:45].[Na+:44]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH:7]([CH2:19][N:41]2[CH2:40][CH2:39][CH:38]([c:35]3[cH:34][cH:33][c:32]([F:31])[cH:37][cH:36]3)[CH2:43][CH2:42]2)[CH2:8][CH:9]([O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 8471TriethylamineHCID 30165Iodide IonHCID 27591364-(4-Fluorophenyl)piperidineHCID 178469390HCID 178469390, compound

Product 1

HCID 178469386ethyl 4-[tert-butyl(dimethyl)silyl]oxy-2-[[4-(4-fluorophenyl)piperidin-1-yl]methyl]cyclopentane-1-carboxylate

Sources & evidence

ORD record
ord-0d901e573d7d48e59b41ea8d3dc57e98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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