Trifluoroacetic acid → 2-fluoro-4-hydroxy-5-[1-(4-methoxybenzyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]benzonitrile
Reaction equation
[CH2:31]([SiH:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[CH3:37].[F:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([C:11]2([OH:30])[C:12](=[O:29])[N:13]([CH2:20][c:21]3[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]3)[c:14]3[cH:15][cH:16][cH:17][cH:18][c:19]32)[c:8]([OH:10])[cH:9]1.[OH:38][C:39]([C:40]([F:41])([F:42])[F:43])=[O:44]>>[F:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([CH:11]2[C:12](=[O:29])[N:13]([CH2:20][c:21]3[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]3)[c:14]3[cH:15][cH:16][cH:17][cH:18][c:19]32)[c:8]([OH:10])[cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-f1dfc0229de341c883c6bf1d935d39df
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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