Pyridine → 4-(3-Trifluoromethyl-benzyl)-piperazine-1-carbonyl chloride
Reaction equation
[Cl:1][C:2]([Cl:3])([O:4][C:5](=[O:6])[O:7][C:8]([Cl:9])([Cl:10])[Cl:11])[Cl:12].[F:19][C:20]([c:21]1[cH:22][c:23]([CH2:24][N:25]2[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]2)[cH:31][cH:32][cH:33]1)([F:34])[F:35].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[cH:13]1[cH:14][cH:15][n:16][cH:17][cH:18]1>>[Cl:1][C:2](=[O:4])[N:28]1[CH2:27][CH2:26][N:25]([CH2:24][c:23]2[cH:22][c:21]([C:20]([F:19])([F:34])[F:35])[cH:33][cH:32][cH:31]2)[CH2:30][CH2:29]1Participants
5
Sources & evidence
- ORD record
- ord-e3d283dfc98942ad868f47444c714388
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…