Methane → 2-(2-Chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenol

HRID 2140258Notes

Reaction equation

HRID 2140258 reaction equation
[C:39].[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([O:7][CH2:8][c:9]3[cH:10][cH:11][cH:12][cH:13][cH:14]3)[cH:15][cH:16][cH:17][cH:18]2)[cH:19][c:20](-[n:24]2[c:25](=[O:36])[n:26]([CH3:35])[c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][c:29]2=[O:30])[c:21]([F:23])[cH:22]1.[H:37][H:38].[Pd:40]>>[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([OH:7])[cH:15][cH:16][cH:17][cH:18]2)[cH:19][c:20](-[n:24]2[c:25](=[O:36])[n:26]([CH3:35])[c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][c:29]2=[O:30])[c:21]([F:23])[cH:22]1

Participants

6

Reactant 5

HCID 297MethaneHCID 8857Ethyl AcetateHCID 23938PalladiumHCID 21933546([2-(2-Chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy)phenoxy]methyl)benzeneHCID 178418361HCID 178418361, compound

Product 1

HCID 121155072-(2-Chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenol

Sources & evidence

ORD record
ord-f7cc44672f81415796aba42714872cec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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