Dimethylformamide → 5-[2-chloro-5-(trifluoromethyl)phenyl]-6-cyclopentyloxy-N-(2-hydroxycyclohexyl)pyridine-3-carboxamide
Reaction equation
[B-:27]([F:28])([F:29])([F:30])[F:31].[CH:49]([N:50]([CH2:51][CH3:52])[CH:53]([CH3:54])[CH3:55])([CH3:56])[CH3:57].[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([C:24](=[O:25])[OH:26])[cH:15][n:16][c:17]2[O:18][CH:19]2[CH2:20][CH2:21][CH2:22][CH2:23]2)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[NH2:58][CH:59]1[CH:60]([OH:65])[CH2:61][CH2:62][CH2:63][CH2:64]1.[O:66]=[CH:67][N:68]([CH3:69])[CH3:70].[n:32]1([O:33][C:34]([N:35]([CH3:36])[CH3:37])=[N+:38]([CH3:39])[CH3:40])[c:41]2[cH:42][cH:43][cH:44][cH:45][c:46]2[n:47][n:48]1>>[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([C:24](=[O:25])[NH:58][CH:59]3[CH:60]([OH:65])[CH2:61][CH2:62][CH2:63][CH2:64]3)[cH:15][n:16][c:17]2[O:18][CH:19]2[CH2:20][CH2:21][CH2:22][CH2:23]2)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-54a9b41eb01e4cffa5edcce5864651cb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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