Dimethylformamide → tert-butyl N-[4-[3-(2-methylbenzimidazol-1-yl)piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

HRID 214073Notes

Reaction equation

HRID 214073 reaction equation
[C:17]([CH3:18])([CH3:19])([CH3:20])[O:21][C:22](=[O:23])[NH:24][CH:25]([CH2:26][C:27](=[O:28])[OH:29])[CH2:30][c:31]1[cH:32][c:33]2[cH:34][cH:35][cH:36][cH:37][c:38]2[cH:39][cH:40]1.[CH3:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH:7]1[CH2:8][NH:9][CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][cH:15][cH:16]2.[CH3:41][N:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[O:72]=[CH:73][N:74]([CH3:75])[CH3:76].[P-:48]([F:49])([F:50])([F:51])([F:52])([F:53])[F:54].[n:55]1([O:56][C:57]([N:58]([CH3:59])[CH3:60])=[N+:61]([CH3:62])[CH3:63])[c:64]2[n:65][cH:66][cH:67][cH:68][c:69]2[n:70][n:71]1>>[CH3:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH:7]1[CH2:8][N:9]([C:27]([CH2:26][CH:25]([NH:24][C:22]([O:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:23])[CH2:30][c:31]3[cH:32][c:33]4[cH:34][cH:35][cH:36][cH:37][c:38]4[cH:39][cH:40]3)=[O:28])[CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][cH:15][cH:16]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 450738432-methyl-1-(piperidin-3-yl)-1H-benzo[d]imidazoleHCID 533979213-(Boc-amino)-4-(2-naphthyl)butyric Acid

Product 1

HCID 66786915tert-butyl N-[4-[3-(2-methylbenzimidazol-1-yl)piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-1dee8dc992814371b689e5190e2b4a5b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…