Diisopropylamine → 2-methyl-N-{3-[5-(3-methyl-5-[[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]oxetan-3-yl]propane-2-sulfinamide
Reaction equation
[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:33][CH:34]([N-:35][CH:36]([CH3:37])[CH3:38])[CH3:39].[CH3:40][C:41]([CH3:42])([CH3:43])[S:44](=[O:45])[N:46]=[C:47]1[CH2:48][O:49][CH2:50]1.[CH3:9][c:10]1[cH:11][c:12]([NH:21][c:22]2[n:23][cH:24][cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[n:27]2)[cH:13][c:14](-[c:16]2[cH:17][n:18][cH:19][s:20]2)[cH:15]1.[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Li+:32].[Li:8]>>[CH3:9][c:10]1[cH:11][c:12]([NH:21][c:22]2[n:23][cH:24][cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[n:27]2)[cH:13][c:14](-[c:16]2[cH:17][n:18][c:19]([C:47]3([NH:46][S:44]([C:41]([CH3:40])([CH3:42])[CH3:43])=[O:45])[CH2:48][O:49][CH2:50]3)[s:20]2)[cH:15]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-47c76456f8ba47aa9cfbfb109b4bf93e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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