Acetyl chloride → 1-[2,6-Dichloro-8-(3-chloro-4-fluorophenylamino)-4H-pyrimido[5,4-d]pyrimidin-3-yl]ethanone
Reaction equation
[C:1]([CH3:2])(=[O:3])[Cl:4].[CH2:26]([N:27]([CH:28]([CH3:29])[CH3:30])[CH:31]([CH3:32])[CH3:33])[CH3:34].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Cl:5][c:6]1[cH:7][c:8]([NH:13][c:14]2[c:15]3[c:16]([n:17][c:18]([Cl:20])[n:19]2)[CH2:21][NH:22][C:23]([Cl:25])=[N:24]3)[cH:9][cH:10][c:11]1[F:12]>>[C:1]([CH3:2])(=[O:3])[N:22]1[CH2:21][c:16]2[c:15]([c:14]([NH:13][c:8]3[cH:7][c:6]([Cl:5])[c:11]([F:12])[cH:10][cH:9]3)[n:19][c:18]([Cl:20])[n:17]2)[N:24]=[C:23]1[Cl:25]Participants
5
Sources & evidence
- ORD record
- ord-24457d3f80134e2ab631631e28426a6b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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