Water → ethyl (3RS,4RS)-3-(2,4-dichlorophenyl)-2-{(1SR,2SR)-2-[(methylsulfonyl)amino]cyclohexyl}-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylate
Reaction equation
[CH3:32][S:33]([Cl:34])(=[O:35])=[O:36].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[CH3:52][C:53]#[N:54].[CH:37]([N:38]([CH:39]([CH3:40])[CH3:41])[CH2:42][CH3:43])([CH3:44])[CH3:45].[NH2:1][CH:2]1[CH:3]([N:8]2[C:9](=[O:31])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]3[CH:16]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[CH:17]2[c:18]2[c:19]([Cl:25])[cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[CH2:4][CH2:5][CH2:6][CH2:7]1.[OH2:55]>>[NH:1]([CH:2]1[CH:3]([N:8]2[C:9](=[O:31])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]3[CH:16]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[CH:17]2[c:18]2[c:19]([Cl:25])[cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[CH2:4][CH2:5][CH2:6][CH2:7]1)[S:33]([CH3:32])(=[O:35])=[O:36]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e8a596fe23de4e4388242be0a6a03ced
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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