Dimethylformamide → N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-3-[4-(6-chloro-pyridin-3-yl)-[1,2,3]triazol-1-yl]-4-methyl-benzamide

HRID 2142886Notes

Reaction equation

HRID 2142886 reaction equation
[CH:41]([N:42]([CH2:43][CH3:44])[CH:45]([CH3:46])[CH3:47])([CH3:48])[CH3:49].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10][n:11](-[c:13]3[cH:14][c:15]([C:16](=[O:17])[OH:18])[cH:19][cH:20][c:21]3[CH3:22])[cH:12]2)[cH:6][n:7]1.[NH2:23][c:24]1[c:25]([O:39][CH3:40])[c:26]([NH:34][S:35](=[O:36])(=[O:37])[CH3:38])[cH:27][c:28]([C:30]([CH3:31])([CH3:32])[CH3:33])[cH:29]1.[O:84]=[CH:85][N:86]([CH3:87])[CH3:88].[OH:74][n:75]1[c:76]2[c:77]([cH:78][cH:79][cH:80][cH:81]2)[n:82][n:83]1.[P-:50]([F:51])([F:52])([F:53])([F:54])([F:55])[F:56].[n:57]1([O:58][C:59]([N:60]([CH3:61])[CH3:62])=[N+:63]([CH3:64])[CH3:65])[c:66]2[n:67][cH:68][cH:69][cH:70][c:71]2[n:72][n:73]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10][n:11](-[c:13]3[cH:14][c:15]([C:16](=[O:18])[NH:23][c:24]4[c:25]([O:39][CH3:40])[c:26]([NH:34][S:35](=[O:36])(=[O:37])[CH3:38])[cH:27][c:28]([C:30]([CH3:31])([CH3:32])[CH3:33])[cH:29]4)[cH:19][cH:20][c:21]3[CH3:22])[cH:12]2)[cH:6][n:7]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 10214710N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamideHCID 210972923-[4-(6-Chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acid

Product 1

HCID 21097171N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-3-[4-(6-chloro-pyridin-3-yl)-[1,2,3]triazol-1-yl]-4-methyl-benzamide

Sources & evidence

ORD record
ord-4111e08667a74f35a7d2a2d36864761f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…