Ethyl Acetate → 5-(4-Boc-piperazin-1-yl)-3-chloro[1,2,4]triazine

HRID 2142906Notes

Reaction equation

HRID 2142906 reaction equation
[C:18](=[O:19])([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[N:25]1[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]1.[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[CH:9]([N:10]([CH:11]([CH3:12])[CH3:13])[CH2:14][CH3:15])([CH3:16])[CH3:17].[Cl:1][c:2]1[n:3][n:4][cH:5][c:6]([Cl:8])[n:7]1.[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[Cl:1][c:2]1[n:3][n:4][cH:5][c:6]([N:28]2[CH2:27][CH2:26][N:25]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:30][CH2:29]2)[n:7]1

Participants

6

Reactant 5

HCID 8857Ethyl AcetateHCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 143452tert-Butyl piperazine-1-carboxylateHCID 122649333,5-Dichloro-1,2,4-triazine

Product 1

HCID 576741865-(4-Boc-piperazin-1-yl)-3-chloro[1,2,4]triazine

Sources & evidence

ORD record
ord-6d6ba31fd5224e0295efaeca0a966687
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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