Hydrochloric Acid → 7-bromo-2-ethoxymethyl-1-{[1-(morpholin-4-ylcarbonyl)piperidin-4-yl]methyl}-1H-imidazo[4,5-c]quinolin-4-amine

HRID 2143120Notes

Reaction equation

HRID 2143120 reaction equation
[Br:3][c:4]1[cH:5][cH:6][c:7]2[c:8]3[c:9]([c:10]([NH2:14])[n:11][c:12]2[cH:13]1)[n:15][c:16]([CH2:25][O:26][CH2:27][CH3:28])[n:17]3[CH2:18][CH:19]1[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1.[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH:45]([Cl:46])([Cl:47])[Cl:48].[ClH:1].[ClH:2].[O:36]1[CH2:37][CH2:38][N:39]([C:42](=[O:43])[Cl:44])[CH2:40][CH2:41]1>>[Br:3][c:4]1[cH:5][cH:6][c:7]2[c:8]3[c:9]([c:10]([NH2:14])[n:11][c:12]2[cH:13]1)[n:15][c:16]([CH2:25][O:26][CH2:27][CH3:28])[n:17]3[CH2:18][CH:19]1[CH2:20][CH2:21][N:22]([C:42]([N:39]2[CH2:38][CH2:37][O:36][CH2:41][CH2:40]2)=[O:43])[CH2:23][CH2:24]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 6212ChloroformHCID 8471TriethylamineHCID 848104-Morpholinecarbonyl chlorideHCID 21984409HCID 21984409, compound

Product 1

HCID 688181177-bromo-2-ethoxymethyl-1-{[1-(morpholin-4-ylcarbonyl)piperidin-4-yl]methyl}-1H-imidazo[4,5-c]quinolin-4-amine

Sources & evidence

ORD record
ord-e204b4e924c34f289aada80c7cd834a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…