Sodium ion → tert-butyl 4-((1-(5-chloro-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazol-7-yl)-2-cyanoethoxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylate

HRID 2143652Notes

Reaction equation

HRID 2143652 reaction equation
[C-:48]#[N:49].[Cl:1][c:2]1[cH:3][c:4]2[cH:5][n:6]([CH2:40][O:41][CH2:42][CH2:43][Si:44]([CH3:45])([CH3:46])[CH3:47])[n:7][c:8]2[c:9]([CH:11]([CH2:12][O:13][S:14]([CH3:15])(=[O:16])=[O:17])[O:18][CH2:19][C:20]2([c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]2)[cH:10]1.[Na+:50].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55]>>[Cl:1][c:2]1[cH:3][c:4]2[cH:5][n:6]([CH2:40][O:41][CH2:42][CH2:43][Si:44]([CH3:45])([CH3:46])[CH3:47])[n:7][c:8]2[c:9]([CH:11]([CH2:12][C:48]#[N:49])[O:18][CH2:19][C:20]2([c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]2)[cH:10]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 5975CyanideHCID 6228DimethylformamideHCID 57545940HCID 57545940, compound

Product 1

HCID 67402367tert-butyl 4-((1-(5-chloro-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazol-7-yl)-2-cyanoethoxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-ed51718824db42c697fa5ba9b54163c5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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