Hydrochloric Acid → 2,6-Difluoro-4-(5-pentylpyrimidin-2-yl)benzonitrile
Reaction equation
[CH3:24][N:25]1[CH2:26][CH2:27][CH2:28][C:29]1=[O:30].[Cl:32][Fe:33]([Cl:34])[Cl:35].[ClH:31].[Cu:21][C:22]#[N:23].[F:1][c:2]1[cH:3][c:4](-[c:10]2[n:11][cH:12][c:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[cH:14][n:15]2)[cH:5][c:6]([F:9])[c:7]1[Br:8].[OH2:36]>>[F:1][c:2]1[cH:3][c:4](-[c:10]2[n:11][cH:12][c:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[cH:14][n:15]2)[cH:5][c:6]([F:9])[c:7]1[C:22]#[N:23]Participants
7
Sources & evidence
- ORD record
- ord-1fba08d082dc4c918135a1ba0c213df1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…