Hydrogen Bromide → 6-chloro-2-methyl-3-{4-[3-(1-piperidinyl)propoxy]phenyl}pyrido[3,4-d]pyrimidin-4(3H)-one
Reaction equation
[Br:40][CH2:41][CH2:42][CH2:43][N:44]1[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]1.[BrH:39].[C:50](=[O:51])([O-:52])[O-:53].[CH3:12][C:13]([O:14][C:15](=[O:16])[CH3:17])=[O:18].[CH3:56][N:57]([CH3:58])[CH:59]=[O:60].[Cl:19][c:20]1[cH:21][c:22]2[c:23]([n:24][c:25]([CH3:36])[n:26](-[c:29]3[cH:30][cH:31][c:32]([OH:35])[cH:33][cH:34]3)[c:27]2=[O:28])[cH:37][n:38]1.[K+:54].[K+:55].[NH2:1][c:2]1[c:3]([C:4]([OH:5])=[O:6])[cH:7][c:8]([Cl:9])[n:10][cH:11]1>>[Cl:19][c:20]1[cH:21][c:22]2[c:23]([n:24][c:25]([CH3:36])[n:26](-[c:29]3[cH:30][cH:31][c:32]([O:35][CH2:41][CH2:42][CH2:43][N:44]4[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]4)[cH:33][cH:34]3)[c:27]2=[O:28])[cH:37][n:38]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-c63d6e4c1c864d46a76de16e698541f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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