Dimethylformamide → HCID 22499798, compound

HRID 2146164Notes

Reaction equation

HRID 2146164 reaction equation
[Br:20][c:21]1[s:22][cH:23][cH:24][n:25]1.[CH:1]1([C:6]([CH2:7][C:8]2=[CH:9][C:10](=[O:16])[O:11][C:12]([CH3:14])([CH3:15])[O:13]2)([C:17]#[CH:18])[OH:19])[CH2:2][CH2:3][CH2:4][CH2:5]1.[CH:26]([NH:27][CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[O:74]=[CH:75][N:76]([CH3:77])[CH3:78].[Pd:33]([Cl:34])[Cl:35].[c:36]1([P:37]([c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[cH:50][cH:51][cH:52][cH:53][cH:54]1.[c:55]1([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:69][cH:70][cH:71][cH:72][cH:73]1>>[CH:1]1([C:6]([CH2:7][C:8]2=[CH:9][C:10](=[O:16])[O:11][C:12]([CH3:14])([CH3:15])[O:13]2)([C:17]#[C:18][c:21]2[s:22][cH:23][cH:24][n:25]2)[OH:19])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 7912DiisopropylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 764302-BromothiazoleHCID 224998026-(2-Cyclopentyl-2-hydroxy-but-3-ynyl)-2,2-dimethyl-[1,3]dioxin-4-one

Product 1

HCID 22499798HCID 22499798, compound

Sources & evidence

ORD record
ord-6d9a84c5315548b0948dcd23da547718
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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