Water → tert-Butyl 4-(2-oxo-2-(thiazol-2-yl)ethyl)piperazine-1-carboxylate
Reaction equation
[Br:6][c:7]1[s:8][cH:9][cH:10][n:11]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:12][O:13][N:14]([C:15]([CH2:16][N:17]1[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]1)=[O:30])[CH3:31].[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[CH3:38][CH2:39][O:40][CH2:41][CH3:42].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1.[OH2:48]>>[c:7]1([C:15]([CH2:16][N:17]2[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]2)=[O:30])[s:8][cH:9][cH:10][n:11]1Participants
8
Sources & evidence
- ORD record
- ord-257111c91c234479b800492088b46760
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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