Tetrahydrofuran → 4-(4-Bromo-2-fluoro-phenylamino)-6-chloro-pyridazine-3-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:19])[c:5]([NH:8][c:9]2[c:10]([C:16](=[O:17])[OH:18])[n:11][n:12][c:13]([Cl:15])[cH:14]2)[cH:6][cH:7]1.[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25](=[N:26][CH:27]([CH3:28])[CH3:29])[NH:30][CH:31]([CH3:32])[CH3:33].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44]>>[Br:1][c:2]1[cH:3][c:4]([F:19])[c:5]([NH:8][c:9]2[c:10]([C:16]([O:17][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:18])[n:11][n:12][c:13]([Cl:15])[cH:14]2)[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-71ddbceb929741c68523235cd53be930
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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