Tetrahydrofuran → HCID 11489280, compound

HRID 2147154Notes

Reaction equation

HRID 2147154 reaction equation
[C:25]([CH3:26])([CH3:27])([CH3:28])[Si:29]([CH3:30])([CH3:31])[O:32][CH:33]1[CH2:34][CH2:35][CH:36]([N:39]=[C:40]=[O:41])[CH2:37][CH2:38]1.[CH2:20]([Li:21])[CH2:22][CH2:23][CH3:24].[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[Cl:1][c:2]1[n:3][cH:4][c:5]([CH2:9][NH:10][c:11]2[c:12]([F:19])[cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]2)[c:6]([Cl:8])[n:7]1.[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:7]1)[N:39]([CH:36]1[CH2:35][CH2:34][CH:33]([O:32][Si:29]([C:25]([CH3:26])([CH3:27])[CH3:28])([CH3:30])[CH3:31])[CH2:38][CH2:37]1)[C:40](=[O:41])[N:10]([c:11]1[c:12]([F:19])[cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]1)[CH2:9]2

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 21939275(2,4-Dichloro-pyrimidin-5-yl-methyl)-(2-fluoro-4-methoxy-phenyl)amineHCID 21939351HCID 21939351, compoundHCID 178418339Butyllithium

Product 1

HCID 11489280HCID 11489280, compound

Sources & evidence

ORD record
ord-307952e14d094cd2be0471058c73ae5b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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