1,2-Dichloroethane → 1-(3-Chloro-phenyl)-1-[2-(3-chloro-phenyl)-5,6-difluoro-2H-indazol-3-yl]-3-cyclohexyl-urea

HRID 2147320Notes

Reaction equation

HRID 2147320 reaction equation
[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH:27]1([N:33]=[C:34]=[O:35])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]1.[Cl:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[n:10](-[c:20]3[cH:21][c:22]([Cl:26])[cH:23][cH:24][cH:25]3)[n:11][c:12]3[cH:13][c:14]([F:19])[c:15]([F:18])[cH:16][c:17]23)[cH:5][cH:6][cH:7]1.[Cl:43][CH2:44][CH2:45][Cl:46]>>[Cl:1][c:2]1[cH:3][c:4]([N:8]([c:9]2[n:10](-[c:20]3[cH:21][c:22]([Cl:26])[cH:23][cH:24][cH:25]3)[n:11][c:12]3[cH:13][c:14]([F:19])[c:15]([F:18])[cH:16][c:17]23)[C:34]([NH:33][CH:27]2[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]2)=[O:35])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 8471TriethylamineHCID 18502Cyclohexyl isocyanateHCID 66905241(3-Chloro-phenyl)-[2-(3-chloro-phenyl)-5,6-difluoro-2H-indazol-3-yl]-amine

Product 1

HCID 451116281-(3-Chloro-phenyl)-1-[2-(3-chloro-phenyl)-5,6-difluoro-2H-indazol-3-yl]-3-cyclohexyl-urea

Sources & evidence

ORD record
ord-dd6a5fc03ed8480d95ad2f57360f4cb5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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