Chloride → 1-(2-hydroxyethyl)-4-[(4-methoxyphenyl)methylsulfanyl]-N-methylpyrrolidine-2-carboxamide

HRID 214743Notes

Reaction equation

HRID 214743 reaction equation
[C:5](=[O:6])([OH:7])[O-:8].[CH3:10][O:11][c:12]1[cH:13][cH:14][c:15]([CH2:16][S:17][CH:18]2[CH2:19][CH:20]([C:23]([NH:24][CH3:25])=[O:26])[NH:21][CH2:22]2)[cH:27][cH:28]1.[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[Cl-:30].[I:1][CH2:2][CH2:3][OH:4].[Na+:29].[Na+:9]>>[CH2:2]([CH2:3][OH:4])[N:21]1[CH:20]([C:23]([NH:24][CH3:25])=[O:26])[CH2:19][CH:18]([S:17][CH2:16][c:15]2[cH:14][cH:13][c:12]([O:11][CH3:10])[cH:28][cH:27]2)[CH2:22]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 6228DimethylformamideHCID 12225IodoethanolHCID 178485509HCID 178485509, compound

Product 1

HCID 148803051-(2-hydroxyethyl)-4-[(4-methoxyphenyl)methylsulfanyl]-N-methylpyrrolidine-2-carboxamide

Sources & evidence

ORD record
ord-c43c012190464acc964dcf59b108cfbb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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