Ethanol → 5-(2-benzyl-2H-indazol-6-yl)-7-{1-[(dimethylamino)acetyl]-1,4,5,6-tetrahydropyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Reaction equation
[CH3:67][CH2:68][OH:69].[CH:40]([N:41]([CH2:42][CH3:43])[CH:44]([CH3:45])[CH3:46])([CH3:47])[CH3:48].[Cl:64][CH2:65][Cl:66].[F:49][C:50]([F:51])([F:52])[C:53]([O:54][C:55](=[O:56])[C:57]([F:58])([F:59])[F:60])=[O:61].[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:24]1[cH:25][cH:26][c:27]3[cH:28][n:29]([CH2:33][c:34]4[cH:35][cH:36][cH:37][cH:38][cH:39]4)[n:30][c:31]3[cH:32]1)[cH:9][c:10]2[C:11]1([OH:23])[CH2:12][N:13]([C:17]([CH2:18][N:19]([CH3:20])[CH3:21])=[O:22])[CH2:14][CH2:15][CH2:16]1.[Na+:63].[OH-:62]>>[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:24]1[cH:25][cH:26][c:27]3[cH:28][n:29]([CH2:33][c:34]4[cH:35][cH:36][cH:37][cH:38][cH:39]4)[n:30][c:31]3[cH:32]1)[cH:9][c:10]2[C:11]1=[CH:12][N:13]([C:17]([CH2:18][N:19]([CH3:20])[CH3:21])=[O:22])[CH2:14][CH2:15][CH2:16]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0c33ab39fe424a12b84d794828f7b3fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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