Dichloromethane → N-{[1,6-Diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}-N'-({3'-[(1-methyl-4-piperidinyl)methyl]-3-biphenylyl}methyl)butanediamide
Reaction equation
[CH2:1]([CH3:2])[n:3]1[n:4][cH:5][c:6]2[c:7]1[n:8][c:9]([CH2:28][CH3:29])[c:10]([CH2:19][NH:20][C:21]([CH2:22][CH2:23][C:24](=[O:25])[OH:26])=[O:27])[c:11]2[NH:12][CH:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1.[CH3:30][N:31]1[CH2:32][CH2:33][CH:34]([CH2:37][c:38]2[cH:39][c:40](-[c:44]3[cH:45][c:46]([CH2:50][NH2:51])[cH:47][cH:48][cH:49]3)[cH:41][cH:42][cH:43]2)[CH2:35][CH2:36]1.[CH3:52][CH2:53][N:54]([CH2:55][CH3:56])[CH2:57][CH3:58].[CH3:62][CH2:63][O:64][C:65]([CH3:66])=[O:67].[Cl:59][CH2:60][Cl:61]>>[CH2:1]([CH3:2])[n:3]1[n:4][cH:5][c:6]2[c:7]1[n:8][c:9]([CH2:28][CH3:29])[c:10]([CH2:19][NH:20][C:21]([CH2:22][CH2:23][C:24](=[O:26])[NH:51][CH2:50][c:46]1[cH:45][c:44](-[c:40]3[cH:39][c:38]([CH2:37][CH:34]4[CH2:33][CH2:32][N:31]([CH3:30])[CH2:36][CH2:35]4)[cH:43][cH:42][cH:41]3)[cH:49][cH:48][cH:47]1)=[O:27])[c:11]2[NH:12][CH:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3e67f3beaed94c4280aa9d2631d2d970
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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