Dimethyl Sulfoxide → tert-Butyl 3-oxo-2-phenylpiperidine-1-carboxylate

HRID 2148339Notes

Reaction equation

HRID 2148339 reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH:19]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[CH:20]([OH:24])[CH2:21][CH2:22][CH2:23]1.[CH3:1][S:2](=[O:3])[CH3:4].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:38][CH2:39][Cl:40].[Cl:5][C:6]([C:7]([Cl:8])=[O:9])=[O:10]>>[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH:19]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[C:20](=[O:24])[CH2:21][CH2:22][CH2:23]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 215840931-t-Butyloxycarbonyl-3-hydroxy-2-phenylpiperidine

Product 1

HCID 11414684tert-Butyl 3-oxo-2-phenylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-3e14332411124fdc95c6d54a1f4bde4d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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