Hydrochloric Acid → Methyl 1-[3-(4-cyanobenzyl)-3H-imidazol-4-ylmethyl]-4-(3-methylbenzyl)piperidine-4-carboxylate

HRID 2148464Notes

Reaction equation

HRID 2148464 reaction equation
[C:21](#[N:22])[c:23]1[cH:24][cH:25][c:26]([CH2:27][n:28]2[cH:29][n:30][cH:31][c:32]2[CH2:33][Cl:34])[cH:35][cH:36]1.[CH3:2][c:3]1[cH:4][c:5]([CH2:6][C:7]2([C:13](=[O:14])[O:15][CH3:16])[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[cH:17][cH:18][cH:19]1.[CH3:46][C:47]#[N:48].[CH:37]([N:38]([CH:39]([CH3:40])[CH3:41])[CH2:42][CH3:43])([CH3:44])[CH3:45].[ClH:1].[ClH:20]>>[CH3:2][c:3]1[cH:4][c:5]([CH2:6][C:7]2([C:13](=[O:14])[O:15][CH3:16])[CH2:8][CH2:9][N:10]([CH2:33][c:32]3[n:28]([CH2:27][c:26]4[cH:25][cH:24][c:23]([C:21]#[N:22])[cH:36][cH:35]4)[cH:29][n:30][cH:31]3)[CH2:11][CH2:12]2)[cH:17][cH:18][cH:19]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 6342AcetonitrileHCID 81531DiisopropylethylamineHCID 97953581-(4-Cyanobenzyl)-5-(chloromethyl)imidazoleHCID 21193292Methyl 4-[(3-methylphenyl)methyl]piperidine-4-carboxylate

Product 1

HCID 15410567Methyl 1-[3-(4-cyanobenzyl)-3H-imidazol-4-ylmethyl]-4-(3-methylbenzyl)piperidine-4-carboxylate

Sources & evidence

ORD record
ord-366bd84933774c779d7438621f8b528a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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