Sodium ion → 7-(2-aminophenyl)-N-(1-azabicyclo[2.2.2]octan-3-yl)-1-benzofuran-2-carboxamide

HRID 2148739Notes

Reaction equation

HRID 2148739 reaction equation
[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([c:9]2[c:10]([NH2:15])[cH:11][cH:12][cH:13][cH:14]2)[O:16]1.[N:19]12[CH2:20][CH:21]([NH:27][C:28](=[O:29])[c:30]3[o:31][c:32]4[c:33]([cH:34]3)[cH:35][cH:36][cH:37][c:38]4[Br:39])[CH:22]([CH2:23][CH2:24]1)[CH2:25][CH2:26]2.[Na+:18].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[OH-:17]>>[c:9]1(-[c:38]2[c:32]3[o:31][c:30]([C:28]([NH:27][CH:21]4[CH2:20][N:19]5[CH2:24][CH2:23][CH:22]4[CH2:25][CH2:26]5)=[O:29])[cH:34][c:33]3[cH:35][cH:36][cH:37]2)[c:10]([NH2:15])[cH:11][cH:12][cH:13][cH:14]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 961HydroxideHCID 6228DimethylformamideHCID 27346522-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)anilineHCID 17982656N-(1-azabicyclo[2.2.2]octan-3-yl)-7-bromo-1-benzofuran-2-carboxamide

Product 1

HCID 768006987-(2-aminophenyl)-N-(1-azabicyclo[2.2.2]octan-3-yl)-1-benzofuran-2-carboxamide

Sources & evidence

ORD record
ord-8d04c7d20c0d41bea8c2b1e8d56c5865
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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