Tetrahydrofuran → 5-(Bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole
Reaction equation
[Br:38][N:39]1[C:40](=[O:41])[CH2:42][CH2:43][C:44]1=[O:45].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[s:5][c:6]1[CH2:7][OH:8].[c:19]1([P:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[CH3:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[s:5][c:6]1[CH2:7][Br:38]Participants
5
Sources & evidence
- ORD record
- ord-ea2791426a1646f2aeafa836fee8209c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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