Tetrahydrofuran → tert-butyl N-(3-(3-hydroxypropyl)phenyl)carbamate

HRID 2149153Notes

Reaction equation

HRID 2149153 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[NH:17][c:18]1[cH:19][c:20]([CH2:24][CH2:25][C:26](=[O:27])[O:28][CH2:29][CH3:30])[cH:21][cH:22][cH:23]1.[CH3:1][CH:2]([CH2:3][AlH:4][CH2:5][CH:6]([CH3:7])[CH3:8])[CH3:9].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[NH:17][c:18]1[cH:19][c:20]([CH2:24][CH2:25][CH2:26][OH:27])[cH:21][cH:22][cH:23]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 14487Diisobutylaluminum hydrideHCID 21994062Ethyl 3-(3-tert-butoxycarbonylaminophenyl)propionate

Product 1

HCID 21993723tert-butyl N-(3-(3-hydroxypropyl)phenyl)carbamate

Sources & evidence

ORD record
ord-b5eccd924d104a89a94e0136f464ecf8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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