Hydrochloric Acid → N-[(4-chloro-2-fluorophenyl)methyl]-1-(6-fluoro-3-pyridinyl)pyrrolidin-3-amine
Reaction equation
[BH4-:32].[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:34][OH:35].[Cl:22][c:23]1[cH:24][c:25]([F:31])[c:26]([CH:27]=[O:28])[cH:29][cH:30]1.[ClH:1].[F:2][c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH:11]([NH2:14])[CH2:12][CH2:13]2)[cH:7][n:8]1.[Na+:33]>>[F:2][c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH:11]([NH:14][CH2:27][c:26]3[c:25]([F:31])[cH:24][c:23]([Cl:22])[cH:30][cH:29]3)[CH2:12][CH2:13]2)[cH:7][n:8]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a64a18cd064d42c1a54871a6a2cede3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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