Hydrochloric Acid → HCID 86638577, compound

HRID 2150836Notes

Reaction equation

HRID 2150836 reaction equation
[BH3:6].[ClH:40].[NH2:7][c:8]1[c:9]([F:39])[cH:10][c:11]([C:14](=[O:15])[N:16]2[CH2:17][CH2:18][N:19]([CH2:22][c:23]3[cH:24][cH:25][c:26]([C:29]([C:30]([F:31])([F:32])[F:33])([C:34]([F:35])([F:36])[F:37])[OH:38])[cH:27][cH:28]3)[CH2:20][CH2:21]2)[cH:12][cH:13]1.[O:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[NH2:7][c:8]1[c:9]([F:39])[cH:10][c:11]([CH2:14][N:16]2[CH2:17][CH2:18][N:19]([CH2:22][c:23]3[cH:24][cH:25][c:26]([C:29]([C:30]([F:31])([F:32])[F:33])([C:34]([F:35])([F:36])[F:37])[OH:38])[cH:27][cH:28]3)[CH2:20][CH2:21]2)[cH:12][cH:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 86638550(4-Amino-3-fluorophenyl)(4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)piperazin-1-yl)methanone

Product 1

HCID 86638577HCID 86638577, compound

Sources & evidence

ORD record
ord-c85ff589b7b6476fb3d7f5a5e5f2466a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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