Dimethylformamide → N-(4-(5-chloro-2-(((3,3-diphenylpropyl)(1-methylethyl)carbamoyl)amino)-1,3-thiazol-4-yl)phenyl)methanesulfonamide

HRID 2150948Notes

Reaction equation

HRID 2150948 reaction equation
[Cl:39][N:40]1[C:41](=[O:42])[CH2:43][CH2:44][C:45]1=[O:46].[O:47]=[CH:48][N:49]([CH3:50])[CH3:51].[c:1]1([CH:7]([CH2:8][CH2:9][N:10]([C:11](=[O:12])[NH:13][c:14]2[s:15][cH:16][c:17](-[c:19]3[cH:20][cH:21][c:22]([NH:25][S:26](=[O:27])(=[O:28])[CH3:29])[cH:23][cH:24]3)[n:18]2)[CH:30]([CH3:31])[CH3:32])[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH2:8][CH2:9][N:10]([C:11](=[O:12])[NH:13][c:14]2[s:15][c:16]([Cl:39])[c:17](-[c:19]3[cH:20][cH:21][c:22]([NH:25][S:26](=[O:27])(=[O:28])[CH3:29])[cH:23][cH:24]3)[n:18]2)[CH:30]([CH3:31])[CH3:32])[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 31398ChlorosuccinimideHCID 251744811-(3,3-Diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea

Product 1

HCID 25175474N-(4-(5-chloro-2-(((3,3-diphenylpropyl)(1-methylethyl)carbamoyl)amino)-1,3-thiazol-4-yl)phenyl)methanesulfonamide

Sources & evidence

ORD record
ord-018902b580b74171868a7a1abb8c719f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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