Chloride → 6-{5-[(4,4-Difluorocyclohexylamino)methyl]naphthalen-1-yloxy}-nicotinamide
Reaction equation
[BH4-:42].[CH3:44][OH:45].[CH:1](=[O:2])[c:3]1[c:4]2[cH:5][cH:6][cH:7][c:8]([O:13][c:14]3[n:15][cH:16][c:17]([C:18](=[O:19])[NH2:20])[cH:21][cH:22]3)[c:9]2[cH:10][cH:11][cH:12]1.[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl-:23].[F:24][C:25]1([F:32])[CH2:26][CH2:27][CH:28]([NH3+:31])[CH2:29][CH2:30]1.[Na+:43].[OH2:46]>>[CH2:1]([c:3]1[c:4]2[cH:5][cH:6][cH:7][c:8]([O:13][c:14]3[n:15][cH:16][c:17]([C:18](=[O:19])[NH2:20])[cH:21][cH:22]3)[c:9]2[cH:10][cH:11][cH:12]1)[NH:31][CH:28]1[CH2:27][CH2:26][C:25]([F:24])([F:32])[CH2:30][CH2:29]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-51b6739867824010bb30358d47dca7bb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…