Pyridine → 17-Ethyl-1,14-dihydroxy-12-[2'-(4"-(2"'-phenyl-2"'-oxo-ethyloxy)-3"-methoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3,1.04,9]octacos-18-ene-2,3,10,16-tetraone
Reaction equation
[CH2:1]([CH3:2])[CH:3]1[C:4](=[O:72])[CH2:5][CH:6]([O:64][Si:65]([C:66]([CH3:67])([CH3:68])[CH3:69])([CH3:70])[CH3:71])[CH:7]([CH3:63])[CH:8]([C:42](=[CH:43][CH:44]2[CH2:45][CH:46]([O:60][CH3:61])[CH:47]([O:50][CH2:51][C:52](=[O:53])[c:54]3[cH:55][cH:56][cH:57][cH:58][cH:59]3)[CH2:48][CH2:49]2)[CH3:62])[O:9][C:10](=[O:41])[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][N:16]2[C:17](=[O:40])[C:18](=[O:39])[C:19]2([OH:38])[CH:20]([CH3:37])[CH2:21][CH:22]([O:35][CH3:36])[CH:23]([CH:24]([O:32][CH3:33])[CH2:25][CH:26]([CH3:31])[CH2:27][C:28]([CH3:30])=[CH:29]1)[O:34]2.[FH:79].[O:80]1[CH2:81][CH2:82][CH2:83][CH2:84]1.[n:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1>>[CH2:1]([CH3:2])[CH:3]1[C:4](=[O:72])[CH2:5][CH:6]([OH:64])[CH:7]([CH3:63])[CH:8]([C:42](=[CH:43][CH:44]2[CH2:45][CH:46]([O:60][CH3:61])[CH:47]([O:50][CH2:51][C:52](=[O:53])[c:54]3[cH:55][cH:56][cH:57][cH:58][cH:59]3)[CH2:48][CH2:49]2)[CH3:62])[O:9][C:10](=[O:41])[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][N:16]2[C:17](=[O:40])[C:18](=[O:39])[C:19]2([OH:38])[CH:20]([CH3:37])[CH2:21][CH:22]([O:35][CH3:36])[CH:23]([CH:24]([O:32][CH3:33])[CH2:25][CH:26]([CH3:31])[CH2:27][C:28]([CH3:30])=[CH:29]1)[O:34]2Participants
5
Reactant 4
HCID 1049Pyridine
HCID 8028Tetrahydrofuran
HCID 14917Hydrofluoric Acid
HCID 5712063917-Ethyl-1-hydroxy-14-(tert-butyldimethylsiloxy)-12-[2'-(4"-(2"'-phenyl-2"'-oxo-ethyloxy)-3"-methoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetraoneProduct 1
Sources & evidence
- ORD record
- ord-a8bd8a34b3d34b45a3333e3629310f25
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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