Citric Acid → 8-Tert-butoxycarbonyl-3-benzyl-1-(4-fluoro-phenyl)-4-oxo-1,3,8-triaza-spiro[4.5]decane
Reaction equation
[Br:28][CH2:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([C:12](=[O:23])[NH:13][CH2:14][N:15]2[c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[CH2:24][CH2:25]1.[H-:27].[Na+:26].[O:49]=[CH:50][N:51]([CH3:52])[CH3:53].[OH:36][C:37]([CH2:38][C:39]([C:40](=[O:41])[OH:42])([CH2:43][C:44](=[O:45])[OH:46])[OH:47])=[O:48]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([C:12](=[O:23])[N:13]([CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[CH2:14][N:15]2[c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[CH2:24][CH2:25]1Participants
7
Sources & evidence
- ORD record
- ord-f263b297c3e24c24a747728fd35d135c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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