Dimethylformamide → 2-(4-(2-(difluoromethyl)pyridin-4-yl)phenyl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Reaction equation
[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[F:1][CH:2]([c:3]1[n:4][cH:5][cH:6][c:7](-[c:9]2[cH:10][cH:11][c:12]([CH2:15][C:16](=[O:17])[OH:18])[cH:13][cH:14]2)[cH:8]1)[F:19].[O:66]=[CH:67][N:68]([CH3:69])[CH3:70].[P-:42]([F:43])([F:44])([F:45])([F:46])([F:47])[F:48].[n:20]1[c:21](-[c:26]2[cH:27][cH:28][c:29]([NH2:32])[n:30][cH:31]2)[cH:22][n:23][cH:24][cH:25]1.[n:49]1([O:50][C:51]([N:52]([CH3:53])[CH3:54])=[N+:55]([CH3:56])[CH3:57])[c:58]2[n:59][cH:60][cH:61][cH:62][c:63]2[n:64][n:65]1>>[F:1][CH:2]([c:3]1[n:4][cH:5][cH:6][c:7](-[c:9]2[cH:10][cH:11][c:12]([CH2:15][C:16](=[O:18])[NH:32][c:29]3[cH:28][cH:27][c:26](-[c:21]4[n:20][cH:25][cH:24][n:23][cH:22]4)[cH:31][n:30]3)[cH:13][cH:14]2)[cH:8]1)[F:19]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-53d8880eff6849729609caf73fcdce7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…