2-Bromopyridine → α-(4-Methoxyphenyl)-2-pyridinemethanol

HRID 2152404Notes

Reaction equation

HRID 2152404 reaction equation
[Br:6][c:7]1[cH:8][cH:9][cH:10][cH:11][n:12]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:13][O:14][c:15]1[cH:16][cH:17][c:18]([CH:19]=[O:20])[cH:21][cH:22]1>>[c:7]1([CH:19]([c:18]2[cH:17][cH:16][c:15]([O:14][CH3:13])[cH:22][cH:21]2)[OH:20])[cH:8][cH:9][cH:10][cH:11][n:12]1

Participants

4

Reactant 3

HCID 79732-BromopyridineHCID 312444-MethoxybenzaldehydeHCID 178418339Butyllithium

Product 1

HCID 99004α-(4-Methoxyphenyl)-2-pyridinemethanol

Sources & evidence

ORD record
ord-0f61ddc2ce53424396041028ad83bd0c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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