Ammonium → 3-O-benzyl 1-O-methyl 6-methyl-3-azabicyclo[3.2.0]heptane-1,3-dicarboxylate

HRID 2152924Notes

Reaction equation

HRID 2152924 reaction equation
[CH3:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[CH3:18][O:19][C:20](=[O:21])[CH:22]1[CH2:23][N:24]([C:31](=[O:32])[O:33][CH2:34][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[CH2:25][CH:26]1[CH:27]([CH2:28][I:29])[CH3:30].[CH3:1][Si:2]([CH3:3])([CH3:4])[N-:5][Si:6]([CH3:7])([CH3:8])[CH3:9].[Cl-:41].[K+:10].[NH4+:42].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[CH3:18][O:19][C:20](=[O:21])[C:22]12[CH2:23][N:24]([C:31](=[O:32])[O:33][CH2:34][c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[CH2:25][CH:26]1[CH:27]([CH3:30])[CH2:28]2

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 813Potassium CationHCID 1140TolueneHCID 8028TetrahydrofuranHCID 3280088Npc316347HCID 691961581-O-benzyl 3-O-methyl 4-(1-iodopropan-2-yl)pyrrolidine-1,3-dicarboxylate

Product 1

HCID 674908333-O-benzyl 1-O-methyl 6-methyl-3-azabicyclo[3.2.0]heptane-1,3-dicarboxylate

Sources & evidence

ORD record
ord-50aec0afa69949b28c220aff5a2d99cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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