Phenylacetic Acid → Tert-butyl 2-phenylacetate

HRID 2153331Notes

Reaction equation

HRID 2153331 reaction equation
[Br:2][c:3]1[cH:4][cH:5][cH:6][cH:7][n+:8]1[CH3:9].[C:10]([CH3:11])([CH3:12])([CH3:13])[OH:14].[CH2:25]([N:26]([CH2:27][CH2:28][CH2:29][CH3:30])[CH2:31][CH2:32][CH2:33][CH3:34])[CH2:35][CH2:36][CH3:37].[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[I-:1].[OH:15][C:16](=[O:17])[CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1>>[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:16](=[O:15])[CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1

Participants

7

Reactant 6

HCID 999Phenylacetic AcidHCID 1140TolueneHCID 6386tert-ButanolHCID 7622TributylamineHCID 30165Iodide IonHCID 8183862-Bromo-1-methylpyridinium

Product 1

HCID 316203Tert-butyl 2-phenylacetate

Sources & evidence

ORD record
ord-308778a85abf45fd8f2416d0b59e914d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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